Croup scores following treatment did not differ and were significantly lower than initial scores for all groups and in each trial. Median duration of hospitalization was similar for children in Trial A (7 and 8 hr), and in Trial B (9 and 9 hr). Duration of hospitalization, reduction in croup scores, and adrenaline usage were evaluated. ![]() In Trial A 60 children received either 0.6 or 0.3 mg/kg dexamethasone syrup in Trial B 60 children received either 0.3 or 0.15 mg/ kg dexamethasone syrup. Baseline characteristics for the two groups in each trial were similar. One hundred and twenty children (age range 6 to 160 months) hospitalized with croup participated. ![]() ![]() The study was conducted in the Emergency Department Observation Ward of a tertiary pediatric hospital. The objective of this study was to compare the efficacy of a single dose of oral dexamethasone of varying sizes in 120 children hospitalized with croup in two sequential double blind, randomized, controlled clinical trials (Trials A and B).
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